Tailor-made 3D-printed phantoms for metrology of quantitative phase imaging systems in biomedical applications

Quantitative Phase Imaging (QPI) has emerged as a powerful tool in advanced biological and pharmacological research. However, there are no standardized reference materials and methods for testing and reporting the metrological performance of QPI systems. In this paper, we introduce a tailor-made 3D-printed phantom derived from phase images of cells and organoids as well as propose and implement the procedures for evaluating and comparing the performance of 2D and 3D QPI systems.

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Published
2025-09-16
DOI
https://doi.org/10.1117/12.3065252
Primary Topic
Advanced X-ray Imaging Techniques
Type
article
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article

Tailor-made 3D-printed phantoms for metrology of quantitative phase imaging systems in biomedical applications

Shun Zhou, Chao Zuo, Piotr Zdańkowski, Małgorzata Kujawińska et al.
Advanced X-ray Imaging Techniques
article

Tailor-made 3D-printed phantoms for metrology of quantitative phase imaging systems in biomedical applications

Shun Zhou, Chao Zuo, Piotr Zdańkowski, Małgorzata Kujawińska, Michał Ziemczonok, Arkadiusz Kuś, Zhuoshi Li
article en

Abstract

Quantitative Phase Imaging (QPI) has emerged as a powerful tool in advanced biological and pharmacological research. However, there are no standardized reference materials and methods for testing and reporting the metrological performance of QPI systems. In this paper, we introduce a tailor-made 3D-printed phantom derived from phase images of cells and organoids as well as propose and implement the procedures for evaluating and comparing the performance of 2D and 3D QPI systems.

Warsaw University of Technology (PL), Nanjing University of Science and Technology (CN)
Openalex Percentile: Top 68%
Advanced X-ray Imaging Techniques
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