A robust deep learning model selection with data augmentation for automatic detection of tessellated fundus images and explainable artificial intelligence based interpretation

A robust deep learning system for automatically classifying retinal fundus images into two classes—normal and tessellated—is presented in this study. Visual Geometry Group – 16 is used as the base model, taking advantage of transfer learning to develop an efficient framework for fundus image classification. The approach uses nine different model architectures and makes use of a dataset of 352 fundus images that was increased to 4865 samples using sophisticated data augmentation techniques. Of these, Model_8 performed the best, achieving a loss of 0.129 % and an impressive accuracy of 99.39 %. The suggested approach ensures higher performance and dependability by combining rigorous data augmentation, efficient preprocessing, and model fine-tuning techniques. Furthermore, Explainable Artificial Intelligence was used to improve the interpretability of the model and visualize important aspects such as features or imposed pathologies in fundus images more clearly. The study offers promising support to ophthalmologists by offering precise automated diagnoses for the early identification and treatment of retinal disorders.

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Publication Details

Journal
Engineering Applications of Artificial Intelligence
Published
2025-09-16
DOI
https://doi.org/10.1016/j.engappai.2025.112316
Citations
1
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
1.36
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A robust deep learning model selection with data augmentation for automatic detection of tessellated fundus images and explainable artificial intelligence based interpretation

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Engineering Applications of Artificial Intelligence
Retinal Imaging and Analysis
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article

A robust deep learning model selection with data augmentation for automatic detection of tessellated fundus images and explainable artificial intelligence based interpretation

Joan Lu, Bharati M. Reshmi, Vinay Kukreja, Qiang Xu, Kachi Anvesh, Murugaperumal Krishnamoorthy, Shanmugasundaram Hariharan
article en
1 citations

Abstract

A robust deep learning system for automatically classifying retinal fundus images into two classes—normal and tessellated—is presented in this study. Visual Geometry Group – 16 is used as the base model, taking advantage of transfer learning to develop an efficient framework for fundus image classification. The approach uses nine different model architectures and makes use of a dataset of 352 fundus images that was increased to 4865 samples using sophisticated data augmentation techniques. Of these, Model_8 performed the best, achieving a loss of 0.129 % and an impressive accuracy of 99.39 %. The suggested approach ensures higher performance and dependability by combining rigorous data augmentation, efficient preprocessing, and model fine-tuning techniques. Furthermore, Explainable Artificial Intelligence was used to improve the interpretability of the model and visualize important aspects such as features or imposed pathologies in fundus images more clearly. The study offers promising support to ophthalmologists by offering precise automated diagnoses for the early identification and treatment of retinal disorders.

Engineering Applications of Artificial IntelligenceVol. 161
Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology (IN), Electronics Corporation of India (IN), University of Huddersfield (GB), Deccan College of Medical Sciences (IN), Centre for Artificial Intelligence and Robotics (IN), Visvesvaraya Technological University (IN), Chitkara University (IN), Leeds Beckett University (GB)
Openalex Percentile: Top 16%
Retinal Imaging and Analysis
1.36
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