[Inhibitory effect of electroacupuncture on microglial activation via Notch1/Hes1 pathway in Parkinson's disease mice].
EA can improve the behavioral performance and protect the dopaminergic neurons in PD mice, its mechanism may relate to the inhibition of Notch1/Hes1-mediated neuroinflammation, thus inhibiting the microglial activation.
Authors
- Huijie Fan (ORCID: https://orcid.org/0000-0003-4298-0679)
- Tiansheng Zhang (ORCID: https://orcid.org/0000-0002-8977-6117)
- Chongyao Hao
- Liran Wang
- Jiangling Jiang (ORCID: https://orcid.org/0000-0002-2056-7157)
- Yunfei Song (ORCID: https://orcid.org/0000-0003-1627-6418)
- Yang Liu (ORCID: https://orcid.org/0000-0002-6627-5002)
- Lei Xu (ORCID: https://orcid.org/0000-0002-7055-7774)
- Zhi Chai (ORCID: https://orcid.org/0000-0002-4586-6807)
- Cun‐Gen Ma (ORCID: https://orcid.org/0000-0003-0049-1658)
- Lixia Yang
Institutions
- Shanxi Medical University (CN)
- Shanxi University (CN)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-09-12
- DOI
- https://doi.org/10.13703/j.0255-2930.20240528-0002
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article