<scp>EBV</scp> ‐associated smooth muscle tumour: a clinicopathological and genetic study of nine cases revealing heterogeneous immune statuses and novel pathogenic mutations

Our study reported nine EBV-SMT cases from heterogeneous immune statuses, with identification of recurrent mutations and pathogenic mutations in some of these tumours, further expanding its clinicopathological and genetic spectrum. Our findings suggest that EBV-SMT cannot be excluded in clinically immunocompetent patients, and further cytogenetic investigations are warranted.

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Publication Details

Journal
Histopathology
Published
2025-09-16
DOI
https://doi.org/10.1111/his.15558
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

EBV ‐associated smooth muscle tumour: a clinicopathological and genetic study of nine cases revealing heterogeneous immune statuses and novel pathogenic mutations

Ting Lan, Xin He, Dan Ren, Hongying Zhang et al.
Histopathology
Viral-associated cancers and disorders
article

EBV ‐associated smooth muscle tumour: a clinicopathological and genetic study of nine cases revealing heterogeneous immune statuses and novel pathogenic mutations

Ting Lan, Xin He, Dan Ren, Hongying Zhang, Qiu Yan, Wenyi Jing, Sheng Qin
article en

Abstract

Our study reported nine EBV-SMT cases from heterogeneous immune statuses, with identification of recurrent mutations and pathogenic mutations in some of these tumours, further expanding its clinicopathological and genetic spectrum. Our findings suggest that EBV-SMT cannot be excluded in clinically immunocompetent patients, and further cytogenetic investigations are warranted.

HistopathologyVol. 87(6)
Harbin Medical University (CN), Sichuan University (CN), Daqing City People's Hospital (CN), West China Hospital of Sichuan University (CN), Sichuan Cancer Hospital (CN)
Openalex Percentile: Top 66%
Viral-associated cancers and disorders
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<scp>EBV</scp> ‐associated smooth muscle tumour: a clinicopathological and genetic study of nine cases revealing heterogeneous immune statuses and novel pathogenic mutations — Ting Lan, Xin He, et al. · Histopathology (2025) | TGRS Research Map | TGRS