The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel–Lindau disease with multiple intramedullary hemangioblastomas: illustrative case

Although a rare metastatic intramedullary CCRCC is difficult to differentiate from comorbid hemangioblastomas in patients with VHLD, it is important to note that the tumor growth rate differs between hemangioblastoma and metastatic CCRCC, which can be followed using sequential MRI. Care must be taken not to dismiss the timing of the removal of metastatic intramedullary tumors. https://thejns.org/doi/10.3171/CASE25459.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-09-15
DOI
https://doi.org/10.3171/case25459
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
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article

The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel–Lindau disease with multiple intramedullary hemangioblastomas: illustrative case

Eiichi Ishikawa, Hiroyoshi Akutsu, Noriaki Sakamoto, Masahide Matsuda et al.
Journal of Neurosurgery Case Lessons
Cancer, Hypoxia, and Metabolism
article

The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel–Lindau disease with multiple intramedullary hemangioblastomas: illustrative case

Eiichi Ishikawa, Hiroyoshi Akutsu, Noriaki Sakamoto, Masahide Matsuda, Hitoshi Aiyama, Takao Tsurubuchi, Hiroyoshi Kino, Shunichiro Miki
article en

Abstract

Although a rare metastatic intramedullary CCRCC is difficult to differentiate from comorbid hemangioblastomas in patients with VHLD, it is important to note that the tumor growth rate differs between hemangioblastoma and metastatic CCRCC, which can be followed using sequential MRI. Care must be taken not to dismiss the timing of the removal of metastatic intramedullary tumors. https://thejns.org/doi/10.3171/CASE25459.

Journal of Neurosurgery Case LessonsVol. 10(11)
University of Tsukuba (JP), Tsukuba Memorial Hospital (JP), Ibaraki Prefectural Central Hospital (JP), Dokkyo Medical University (JP)
Openalex Percentile: Top 69%
Cancer, Hypoxia, and Metabolism
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The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel–Lindau disease with multiple intramedullary hemangioblastomas: illustrative case — Eiichi Ishikawa, Hiroyoshi Akutsu, et al. · Journal of Neurosurgery Case Lessons (2025) | TGRS Research Map | TGRS