Chronic endometritis diagnosis and fertility outcomes: an old unresolved question
Chronic endometritis is a reversible cause of infertility and remains a clinical and biologic challenge even using hysteroscopy and conventional histology and relies on the presence of plasma cells in immunohistochemistry. Our results underline the low accuracy of hysteroscopy and conventional histology to assess chronic endometritis, thus supporting the systematic use of CD138 immunostaining in infertile women even in the case of normal endometrium. Moreover, pregnancy rate seems enhanced by antibiotic therapy.
Authors
- Nathalie Massin
- Yohann Dabi
- Jérôme Bouaziz (ORCID: https://orcid.org/0000-0002-4674-8626)
- Émile Daraï (ORCID: https://orcid.org/0000-0003-2083-7097)
- Johanna Ilic (ORCID: https://orcid.org/0000-0003-4661-3112)
- Jessica Issa
- Justine Varinot (ORCID: https://orcid.org/0000-0001-5602-3058)
- Cyril Touboul (ORCID: https://orcid.org/0000-0002-9149-1663)
- Rana Mitri-Frangieh
- Bassam Haddad
Institutions
- Université Pierre Mendès France (FR)
- Sorbonne Université (FR)
- Center Point (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Intercommunal de Créteil (FR)
- Hôpital Tenon (FR)
Publication Details
- Journal
- Reproduction and Fertility
- Published
- 2025-09-15
- DOI
- https://doi.org/10.1530/raf-25-0016
- Citations
- 1
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.70