Rare Neuroendocrine Tumor of the Bladder: A Case Report

Well-differentiated neuroendocrine tumors (WD-NETs) of the bladder are notably rare, representing only a small subset of neuroendocrine malignancies in this organ. We present a case of an asymptomatic 67-year-old Hispanic male in whom a WD-NET was incidentally identified during routine surveillance cystoscopy, six months following anterior urethroplasty with a buccal mucosal graft. The patient underwent two transurethral resections of the bladder tumor (TURBT). This case highlights the diagnostic challenges associated with WD-NETs given their rarity and reinforces the need for clinical awareness, even in patients without typical risk factors or symptoms.

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Publication Details

Journal
Cureus
Published
2025-09-12
DOI
https://doi.org/10.7759/cureus.92132
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
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article

Rare Neuroendocrine Tumor of the Bladder: A Case Report

Omar Soto-Avilés, Manuel Pizarro-Mondesir, Laritza Fernandez-Claro, Francisco Baralt-Nazario
Cureus
Neuroendocrine Tumor Research Advances
article

Rare Neuroendocrine Tumor of the Bladder: A Case Report

Omar Soto-Avilés, Manuel Pizarro-Mondesir, Laritza Fernandez-Claro, Francisco Baralt-Nazario
article en

Abstract

Well-differentiated neuroendocrine tumors (WD-NETs) of the bladder are notably rare, representing only a small subset of neuroendocrine malignancies in this organ. We present a case of an asymptomatic 67-year-old Hispanic male in whom a WD-NET was incidentally identified during routine surveillance cystoscopy, six months following anterior urethroplasty with a buccal mucosal graft. The patient underwent two transurethral resections of the bladder tumor (TURBT). This case highlights the diagnostic challenges associated with WD-NETs given their rarity and reinforces the need for clinical awareness, even in patients without typical risk factors or symptoms.

CureusVol. 17(9)
University of Puerto Rico, Medical Sciences Campus (PR), Central University of the Caribbean (PR), Bayamón Central University (PR), University of Puerto Rico at Bayamón (PR)
Openalex Percentile: Top 66%
Neuroendocrine Tumor Research Advances
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Rare Neuroendocrine Tumor of the Bladder: A Case Report — Omar Soto-Avilés, Manuel Pizarro-Mondesir, et al. · Cureus (2025) | TGRS Research Map | TGRS