Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model
This study is the first to determine that luteolin ameliorates CPP via the Toll-like receptor signaling pathway. These findings enhance our understanding of luteolin's pharmacological actions and support its potential role in CPP treatment.
Authors
- Enze Lei (ORCID: https://orcid.org/0000-0001-8977-5758)
- Shanshan Bai (ORCID: https://orcid.org/0000-0003-2439-6444)
- Xiaofan Wu (ORCID: https://orcid.org/0000-0002-6363-1008)
- Zhijian Zha (ORCID: https://orcid.org/0009-0005-4636-7363)
- Tiantian Huang (ORCID: https://orcid.org/0000-0002-9088-6313)
- Jianzhong Liu (ORCID: https://orcid.org/0000-0002-1673-2439)
- Zifeng Wang (ORCID: https://orcid.org/0000-0001-7400-5224)
- Tao Lu (ORCID: https://orcid.org/0000-0002-5948-4762)
- Yao Chen (ORCID: https://orcid.org/0000-0002-2336-3432)
- Hui Li (ORCID: https://orcid.org/0000-0001-6396-4833)
- Yan Cai (ORCID: https://orcid.org/0000-0003-0015-5072)
Institutions
- Hubei University of Chinese Medicine (CN)
- Hubei Provincial Hospital of Traditional Chinese Medicine (CN)
- Wuhan Ship Development & Design Institute (CN)
- Wuhan Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3389/fendo.2025.1666932
- Citations
- 2
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 3.63