In vitro and in vivo osteogenesis of rat adipose-derived stem cells combined with calcium alginate gel scaffold induced by calcitonin gene-related peptide
These findings indicate that CGRP can induce ADSCs combined with CaAlg scaffolds to form tissue-engineered bone <i>in vivo</i>, with CGRP and CaAlg scaffolds showing a synergistic effect on promoting ADSC osteogenic differentiation.
Authors
- Jian‐Xian Lin (ORCID: https://orcid.org/0000-0002-5006-4454)
- Changzhi Huang
- Xiaoyong Wang (ORCID: https://orcid.org/0000-0001-6048-6100)
- Xiaofeng Liu (ORCID: https://orcid.org/0000-0003-4576-9094)
- Liang Lin (ORCID: https://orcid.org/0000-0003-2248-3755)
- Shimin Zhang
- Ning Xu (ORCID: https://orcid.org/0000-0002-3873-0506)
Institutions
- Fujian Medical University (CN)
- Ningde Normal University (CN)
- The 180th Hospital of PLA (CN)
- Shanghai Sixth People's Hospital (CN)
- Putian University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3389/fcell.2025.1669459
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00