Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning
CD48 was identified as a potential early biomarker for the transition from AS to HF, which may offer new insights for risk stratification and early intervention in disease progression.
Authors
- Fugui Zhang
- Lin-Meng Wang
- Lihua Ni (ORCID: https://orcid.org/0000-0002-0456-3279)
- Juan Du (ORCID: https://orcid.org/0000-0001-7649-9571)
- Huabo Li
- Zhou Ke (ORCID: https://orcid.org/0009-0007-9931-1616)
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Minda Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3389/fgene.2025.1587274
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00