Age-enhanced MAGIC algorithm predicts mortality in pediatric aGVHD: a multicenter study
The Panel 2 score effectively predicted NRM, OS, and treatment response in pediatric aGVHD. Incorporating age ≥12 years further enhanced risk stratification, enabling clear separation between HR and LR groups. These findings support the potential clinical utility of this combined model and warrant validation in larger, international pediatric cohorts.
Authors
- Dao Wen Wang (ORCID: https://orcid.org/0000-0002-9774-3980)
- Shaoyang Deng
- Shan He (ORCID: https://orcid.org/0000-0002-0196-7278)
- W. S. Cheng (ORCID: https://orcid.org/0009-0008-5915-9565)
- Zhang Ben-shan
- Na Song (ORCID: https://orcid.org/0000-0001-7793-570X)
- Hao Xiong (ORCID: https://orcid.org/0000-0002-1932-9282)
- Ri Xu
Institutions
- Central South University (CN)
- Annoroad Gene Technology (China) (CN)
- Hunan Children's Hospital (CN)
- Wuhan Children's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1660861
- Primary Topic
- Retinopathy of Prematurity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00