Worldwide patterns and trends in childhood and adolescent brain cancers, 1990–2021: insights from the global burden of disease study 2021

While advancements in medical care have contributed to the reduction of CABC mortality in high-SDI regions, persistent disparities in Low-SDI areas necessitate urgent interventions. Targeted strategies-such as scalable diagnostic tools, establishment of regional treatment hubs, and equitable financial support through global initiatives like the WHO Childhood Cancer Initiative-are crucial to addressing these disparities. This study underscored the dual challenge of enhancing survivorship outcomes in high-income settings while rectifying systemic healthcare gaps in low-resource regions to promote global equity in pediatric oncology care.