Immunization route-mediated differences in long-term maturation of humoral immune response induced by adenovirus vector-based COVID-19 vaccine Sputnik V in nonhuman primates
The present study provides valuable information about distinct features of the long-term postvaccination humoral immune response in nonhuman primates induced by adenoviral COVID-19 vaccine administered by the intramuscular and intranasal routes commonly used in clinical practice.
Authors
- Alina S. Erokhova (ORCID: https://orcid.org/0000-0003-2866-0329)
- Gintsburg Al (ORCID: https://orcid.org/0000-0003-1769-5059)
- Denis Y. Logunov (ORCID: https://orcid.org/0000-0003-4035-6581)
- Anna V. Kovyrshina (ORCID: https://orcid.org/0000-0002-8757-7026)
- Andrey V. Moroz (ORCID: https://orcid.org/0000-0002-2268-5720)
- Aydar A. Ishmukhametov (ORCID: https://orcid.org/0000-0001-6130-4145)
- Fatima M. Izhaeva
- Artem Y. Shelkov (ORCID: https://orcid.org/0000-0002-5491-6802)
- I. B. Esmagambetov (ORCID: https://orcid.org/0000-0002-2063-2449)
- Ilya Gordeychuk (ORCID: https://orcid.org/0000-0002-4551-7535)
- Tatiana V. Gulyaeva (ORCID: https://orcid.org/0000-0003-2486-6952)
- Dmitry V. Shcheblyakov (ORCID: https://orcid.org/0000-0002-1289-3411)
- Inna V. Dolzhikova (ORCID: https://orcid.org/0000-0003-2548-6142)
- Amir I. Tukhvatulin (ORCID: https://orcid.org/0000-0001-8506-2339)
- Darya Avdoshina (ORCID: https://orcid.org/0000-0001-8168-5969)
- Ilya D. Zorkov (ORCID: https://orcid.org/0000-0001-8311-2283)
- Anna A. Iliukhina (ORCID: https://orcid.org/0000-0003-0728-5478)
- Alina S. Dzharullaeva (ORCID: https://orcid.org/0000-0003-1743-0798)
- Olga V. Zubkova (ORCID: https://orcid.org/0000-0001-7893-8419)
- Ekaterina Bayurova
- S. A. Gulyaev
- Alla Zhitkevich
Institutions
- Sechenov University (RU)
- Ministry of Health of the Russian Federation (RU)
- Chumakov Institute of Poliomyelitis and Viral Encephalitides (RU)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1634187
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00