6-gingerol promotes apoptosis of ovarian cancer cells through miR-506/Gli3 signaling pathway activation

Our results indicate that gingerol promoted the upregulation of miR-506, leading to the induction of apoptosis in ovarian cancer cells. This study supports the potential of 6-gingerol-based therapy for ovarian malignancies.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-09-12
DOI
https://doi.org/10.3389/fonc.2025.1547771
Primary Topic
Ginger and Zingiberaceae research
Type
article
Field-Weighted Citation Impact
0.00
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article

6-gingerol promotes apoptosis of ovarian cancer cells through miR-506/Gli3 signaling pathway activation

Xiao-Ju He, Jun Xiong, Huan Li, Xiao-Qing Tan et al.
Frontiers in Oncology
Ginger and Zingiberaceae research
article

6-gingerol promotes apoptosis of ovarian cancer cells through miR-506/Gli3 signaling pathway activation

Xiao-Ju He, Jun Xiong, Huan Li, Xiao-Qing Tan, Xue‐Xin Cheng, Hui Jiang, Hong-Hu Wu
article en

Abstract

Our results indicate that gingerol promoted the upregulation of miR-506, leading to the induction of apoptosis in ovarian cancer cells. This study supports the potential of 6-gingerol-based therapy for ovarian malignancies.

Frontiers in OncologyVol. 15
Nanchang University (CN), Second Affiliated Hospital of Nanchang University (CN)
Openalex Percentile: Top 67%
Ginger and Zingiberaceae research
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6-gingerol promotes apoptosis of ovarian cancer cells through miR-506/Gli3 signaling pathway activation — Xiao-Ju He, Jun Xiong, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS