Air pollution-related immune gene prognostic signature for hepatocellular carcinoma: network toxicology, machine learning and multi-omics analysis
We identified key APIGs and constructed a robust APIG-based prognostic signature for HCC. CDC25C was a key target through which APs impact HCC and multiple other cancers.
Authors
- Lei Pu
- Peng Sun (ORCID: https://orcid.org/0000-0003-1365-3855)
- Pu Cheng (ORCID: https://orcid.org/0000-0001-6358-5219)
- Xiaoyan Zhang (ORCID: https://orcid.org/0000-0002-9664-1560)
Institutions
- Shanghai University of Sport (CN)
- East China Normal University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1638445
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04