Atypical Presentation of Meningococcemia as Gastroenteritis in an Adult: A Case Report

Meningococcal disease is a life-threatening infection that can present with diverse and sometimes atypical manifestations, making early diagnosis challenging. We report the case of a 29-year-old man who presented with acute gastrointestinal symptoms, raising suspicion for gastroenteritis. Blood cultures later identified <i>Neisseria meningitidis</i> serogroup W135, confirming a diagnosis of meningococcemia. Unlike the typical presentation of meningococcal disease in adults, which often features fever, hypotension, myalgias, and a characteristic petechial rash, this patient exhibited predominantly gastrointestinal manifestations without neurologic signs or rash, leading to an early diagnostic challenge. Prompt recognition and empirical antibiotic treatment resulted in rapid clinical improvement and prevention of complications. This case underscores the importance of maintaining a high index of suspicion for meningococcemia in adults presenting with sepsis, even in the absence of classic features, as early intervention remains critical to improving outcomes.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-09-12
DOI
https://doi.org/10.7759/cureus.92126
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Atypical Presentation of Meningococcemia as Gastroenteritis in an Adult: A Case Report

Tarek Ibrahim, Abdulrahman Saad, Abdulqadir J. J. Nashwan, Usamah Al‐Anbagi
Cureus
Bacterial Infections and Vaccines
article

Atypical Presentation of Meningococcemia as Gastroenteritis in an Adult: A Case Report

Tarek Ibrahim, Abdulrahman Saad, Abdulqadir J. J. Nashwan, Usamah Al‐Anbagi
article en

Abstract

Meningococcal disease is a life-threatening infection that can present with diverse and sometimes atypical manifestations, making early diagnosis challenging. We report the case of a 29-year-old man who presented with acute gastrointestinal symptoms, raising suspicion for gastroenteritis. Blood cultures later identified <i>Neisseria meningitidis</i> serogroup W135, confirming a diagnosis of meningococcemia. Unlike the typical presentation of meningococcal disease in adults, which often features fever, hypotension, myalgias, and a characteristic petechial rash, this patient exhibited predominantly gastrointestinal manifestations without neurologic signs or rash, leading to an early diagnostic challenge. Prompt recognition and empirical antibiotic treatment resulted in rapid clinical improvement and prevention of complications. This case underscores the importance of maintaining a high index of suspicion for meningococcemia in adults presenting with sepsis, even in the absence of classic features, as early intervention remains critical to improving outcomes.

CureusVol. 17(9)
Ministry of Public Health (QA), Hamad General Hospital (QA), Hamad Medical Corporation (QA)
Openalex Percentile: Top 77%
Bacterial Infections and Vaccines
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.