A Rare Case of Giant Retroperitoneal Dedifferentiated Liposarcoma: A Case Report

Retroperitoneal liposarcoma is a type of tumor originating from various non-specific organs in the retroperitoneum and is the most common retroperitoneal tumor. Due to its deep location and insidious onset, early clinical manifestations are not obvious, and it is generally discovered only when the tumor is large, causing complications by invading or pressing on nearby tissues and organs. This article reports a case of a patient with a giant retroperitoneal liposarcoma who underwent radical resection. Postoperative pathological examination confirmed it to be a dedifferentiated liposarcoma. This case details the surgical removal of a giant retroperitoneal dedifferentiated liposarcoma and the successful postoperative recovery of the patient, vividly illustrating the surgical skills and perioperative management strategies required to handle such challenging cases. This case provides valuable surgical experience for managing giant retroperitoneal liposarcoma and highlights the practical significance of a surgery-focused comprehensive treatment in improving the quality of life for patients.

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Publication Details

Journal
Cureus
Published
2025-09-12
DOI
https://doi.org/10.7759/cureus.92142
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

A Rare Case of Giant Retroperitoneal Dedifferentiated Liposarcoma: A Case Report

Hui Luo, Wei Ding, Yufei Wang
Cureus
Sarcoma Diagnosis and Treatment
article

A Rare Case of Giant Retroperitoneal Dedifferentiated Liposarcoma: A Case Report

Hui Luo, Wei Ding, Yufei Wang
article en

Abstract

Retroperitoneal liposarcoma is a type of tumor originating from various non-specific organs in the retroperitoneum and is the most common retroperitoneal tumor. Due to its deep location and insidious onset, early clinical manifestations are not obvious, and it is generally discovered only when the tumor is large, causing complications by invading or pressing on nearby tissues and organs. This article reports a case of a patient with a giant retroperitoneal liposarcoma who underwent radical resection. Postoperative pathological examination confirmed it to be a dedifferentiated liposarcoma. This case details the surgical removal of a giant retroperitoneal dedifferentiated liposarcoma and the successful postoperative recovery of the patient, vividly illustrating the surgical skills and perioperative management strategies required to handle such challenging cases. This case provides valuable surgical experience for managing giant retroperitoneal liposarcoma and highlights the practical significance of a surgery-focused comprehensive treatment in improving the quality of life for patients.

CureusVol. 17(9)
Southwest Medical University (CN)
Openalex Percentile: Top 64%
Sarcoma Diagnosis and Treatment
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A Rare Case of Giant Retroperitoneal Dedifferentiated Liposarcoma: A Case Report — Hui Luo, Wei Ding, et al. · Cureus (2025) | TGRS Research Map | TGRS