Thyrotoxicosis Triggering Takotsubo Cardiomyopathy and Acute Coronary Syndrome: A Case of Severe Cardiovascular Manifestations in Hyperthyroidism

Hyperthyroidism can lead to serious cardiovascular complications, including arrhythmias, high-output heart failure, and myocardial ischemia. Thyrotoxicosis, a hypermetabolic emergency, may mimic or exacerbate acute coronary syndrome (ACS) and, though rare, has been associated with takotsubo cardiomyopathy. We present a case of a 54-year-old thyrotoxic female without significant cardiovascular history who presented with atypical chest pain complicated by both takotsubo cardiomyopathy and myocardial infarction. This case not only emphasizes the diagnostic challenge posed by thyroid-induced cardiac dysfunctions but also highlights the importance of multidisciplinary management in these patients.