Reassessing D-Dimer Cut-Offs for Pulmonary Embolism: A Path Toward Safer and More Cost-Effective Diagnosis
This study highlights the potential to improve the diagnosis of pulmonary embolism (PE) by adjusting the D-dimer cut-off. By increasing the cut-off, we were able to enhance specificity while maintaining sensitivity, leading to fewer unnecessary imaging tests. These results suggest that refining diagnostic thresholds can improve the accuracy of PE detection, reduce patient exposure to unnecessary procedures, and better allocate healthcare resources.
Authors
- Ahmad Al-Alwan
- MONTASER ALRJOOB
- Charmee Vyas
- Husam Bader
- Amer Abu-Shanab (ORCID: https://orcid.org/0000-0002-0986-9699)
- Apurva Ketkar
- Sohini Sarkar (ORCID: https://orcid.org/0000-0002-3855-7467)
- Doantrang Du
- A. Alkhatib
- Zain Albdour (ORCID: https://orcid.org/0009-0008-6946-1063)
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Jordan (JO)
- Monmouth Medical Center (US)
Publication Details
- Journal
- Journal of Community Hospital Internal Medicine Perspectives
- Published
- 2025-09-12
- DOI
- https://doi.org/10.55729/2000-9666.1536
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00