The Effect of Hyaluronic Acid Gel Injection on The Reconstruction of Deficient Interdental Papilla

Background and objectives: The use of hyaluronic acid as injectable gel into gaps where interdental papillae are absent can refill black triangles. This study aims to evaluate the effects of two concentrations of hyaluronic acid on papilla regeneration by measuring the black triangle height. Methods: This prospective interventional study carried out in Khanzad specialized dental center in Erbil city-Kurdistan region/Iraq through the period of 6 months from 1st of March 2023, to 1st of September 2023 on a sample of 20 patients with deficient tissue between their central and lateral incisors. A split-mouth technique was employed for the administration of hyaluronic acid with concentrations of 22mg/ml and 20mg/ml. Each region received three injections each three weeks. Participants were re-evaluated after three and six months. An ANOVA test was used to compare mean values. Results: There was a statistically significant disparity in black triangle height between the groups (p = 0.013) after three months. Later, after a duration of six months, there was compelling evidence of a distinction between the two groups (p = 0.004). For the 22mg\ml group, full coverage was achieved in six months by 60% (12 out of 20) while for the 20mg\ml group it was only 40% (8 out of 20). Conclusions: Both concentrations showed significant effect on reconstruction of missing interdental papilla with more effect in the 22 mg\ml group (p < 0.01).