The Value of Mean Platelet Volume as a Predictor in Preeclampsia

Background and Objectives: Preeclampsia, a pregnancy-specific disorder, is a major cause of fetal and maternal morbidity and mortality due to endothelial dysfunction and coagulation system activation. This study aimed to evaluate the complete blood counts and assess the mean platelet volume value in preeclamptic patients. Methods: This retrospective -sectional study was carried out in Sulaimaniyah Maternity Teaching Hospital, in Kurdistan Region, Northern Iraq, for a period of one year from August 2022 to August 2023. A sample of 210 women was taken, 109 affected by Preeclampsia and 100 “normotensive” women the complete blood picture at the late 1st trimester and early 2nd trimester was reviewed for both groups and mean platelet volume was calculated and compared between the two groups. Results: A significant difference was observed in the value of Mean Platelet Volume in early pregnancy of women with Preeclampsia compared to those of normotensive women, with a sensitivity of 68% a specificity of 63 %, and an overall accuracy of 66%, a p-value of 0.001. There were also significant associations between Intrauterine Growth Restriction formation and high Mean Platelet Volume of the 109 women with preeclampsia 27 of them had both Preeclampsia and intra formation. However, no significant differences were seen in the modes of delivery and parity. Conclusion: The availability and low cost of a complete blood count make the detection of high Mean Platelet Volume a simple measure to eventually predict the development of Preeclampsia and thus leading to earlier treatment and interventions, making its complications less likely.