A Pilot Study Using Microbial Glycolipid Signatures to Diagnose Nosocomial Ventriculitis

This study highlights the potential of FLAT followed by MALDI-TOF MS as a valuable tool for expediting ventriculitis pathogen identification. By bypassing the need for culture and delivering results in about an hour, this approach could significantly reduce turnaround times and potentially improve patient outcomes.

Authors

James B. Doub (ORCID: https://orcid.org/0000-0002-4977-0968)
Robert K. Ernst (ORCID: https://orcid.org/0000-0001-5016-8694)
Ian P. O’Keefe (ORCID: https://orcid.org/0000-0003-1151-3242)
Nicole Putnam (ORCID: https://orcid.org/0000-0002-3337-2105)

Institutions

University of Maryland, Baltimore (US)
University of Baltimore (US)

Publication Details

Journal: Rapid Communications in Mass Spectrometry
Published: 2025-09-15
DOI: https://doi.org/10.1002/rcm.10138
Primary Topic: Bacterial Identification and Susceptibility Testing
Type: article
Field-Weighted Citation Impact: 0.00

Funders

University of Maryland, Baltimore County
National Institutes of Health

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article

A Pilot Study Using Microbial Glycolipid Signatures to Diagnose Nosocomial Ventriculitis

James B. Doub, Robert K. Ernst, Ian P. O’Keefe, Nicole Putnam

Sep 15, 2025

Rapid Communications in Mass Spectrometry

Bacterial Identification and Susceptibility Testing

article

A Pilot Study Using Microbial Glycolipid Signatures to Diagnose Nosocomial Ventriculitis

James B. Doub, Robert K. Ernst, Ian P. O’Keefe, Nicole Putnam

September 15, 2025article en

Abstract

This study highlights the potential of FLAT followed by MALDI-TOF MS as a valuable tool for expediting ventriculitis pathogen identification. By bypassing the need for culture and delivering results in about an hour, this approach could significantly reduce turnaround times and potentially improve patient outcomes.

Rapid Communications in Mass SpectrometryVol. 39(24)

University of Maryland, Baltimore (US), University of Baltimore (US)

University of Maryland, Baltimore County, National Institutes of Health

Openalex Percentile: Top 72%

Bacterial Identification and Susceptibility Testing

DOI Open Access PDF OpenAlex

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A Pilot Study Using Microbial Glycolipid Signatures to Diagnose Nosocomial Ventriculitis — James B. Doub, Robert K. Ernst, et al. · Rapid Communications in Mass Spectrometry (2025) | TGRS Research Map | TGRS