Integrating machine learning for the identification of ubiquitination-associated genes in moyamoya disease
Potential therapeutic drugs, including benzohydroxamic acid and PKC-beta inhibitors, were predicted to target these key genes, suggesting new avenues for MMD treatment.
Authors
- Shihao He (ORCID: https://orcid.org/0000-0002-2522-8656)
- Hongchuan Niu
- Xilong Wang (ORCID: https://orcid.org/0009-0006-5053-4053)
- Yuanli Zhao (ORCID: https://orcid.org/0000-0002-3263-6797)
- Zhenyu Zhou (ORCID: https://orcid.org/0000-0002-7934-4425)
- Yutong Liu (ORCID: https://orcid.org/0000-0001-6507-7090)
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Tian Tan Hospital (CN)
- Peking University International Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fneur.2025.1653433
- Citations
- 1
- Primary Topic
- Moyamoya disease diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.67