The mediating role of Body Roundness Index in the association between Life’s Crucial 9 and infertility: a cross-sectional study using NHANES 2013–2018

There is a significant negative correlation between LC9 and infertility, with BRI playing a partial mediating role. These findings highlight the importance of cardiovascular health and obesity management in reproductive health and suggest that reducing central obesity may lower the risk of infertility. Further research is needed on potential intervention strategies targeting metabolic and cardiovascular health to prevent infertility.

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Publication Details

Journal
Frontiers in Nutrition
Published
2025-09-16
DOI
https://doi.org/10.3389/fnut.2025.1605601
Primary Topic
Assisted Reproductive Technology and Twin Pregnancy
Type
article
Field-Weighted Citation Impact
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article

The mediating role of Body Roundness Index in the association between Life’s Crucial 9 and infertility: a cross-sectional study using NHANES 2013–2018

Ling Zhang, Qianyi Zhong, Ying Wang, Lei Bao et al.
Frontiers in Nutrition
Assisted Reproductive Technology and Twin Pregnancy
article

The mediating role of Body Roundness Index in the association between Life’s Crucial 9 and infertility: a cross-sectional study using NHANES 2013–2018

Ling Zhang, Qianyi Zhong, Ying Wang, Lei Bao, Jianping Xu, Lin Gao
article en

Abstract

There is a significant negative correlation between LC9 and infertility, with BRI playing a partial mediating role. These findings highlight the importance of cardiovascular health and obesity management in reproductive health and suggest that reducing central obesity may lower the risk of infertility. Further research is needed on potential intervention strategies targeting metabolic and cardiovascular health to prevent infertility.

Frontiers in NutritionVol. 12
Taizhou Central Hospital (CN), Taizhou University (CN)
Openalex Percentile: Top 65%
Assisted Reproductive Technology and Twin Pregnancy
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