Maternal high-salt intake induces sex-specific liver injury in offspring: integrative transcriptomic and therapeutic investigation
Maternal high-salt intake induces sex-specific structural and molecular liver injury in offspring, highlighting the developmental origins of liver disease. These findings emphasize the importance of maternal nutrition in shaping offspring hepatic health and suggest potential pharmacological strategies to counteract early-life dietary insults.
Authors
- Wanyu Song
- Li Wang (ORCID: https://orcid.org/0000-0002-6727-5207)
- Haiying Wu (ORCID: https://orcid.org/0009-0009-5083-2722)
- Rui Chen (ORCID: https://orcid.org/0000-0003-4671-4538)
- Xiuli Chen (ORCID: https://orcid.org/0000-0002-2576-4256)
Institutions
- Henan Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fnut.2025.1657934
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00