Diagnostic Utility of Serum CEA and Ca 19.9 as Triage Tools for Predicting Metastatic Disease in Gallbladder Cancer: A Sub-analysis from a Prospective Observational Study
Elevated serum CEA and Ca 19.9 adjusted for jaundice status are strong indicators of metastatic gallbladder cancer at presentation. This real-world percentile-based approach offers a rapid, low-cost diagnostic adjunct for early triage in resource-limited settings. The findings provide context-sensitive thresholds that may aid timely treatment decisions in high-burden regions.
Authors
- S. N. Singh (ORCID: https://orcid.org/0000-0001-5707-4148)
- Akash Srivastava (ORCID: https://orcid.org/0000-0002-5959-3926)
- Barun Kumar (ORCID: https://orcid.org/0000-0002-2562-1714)
- Kumar Vineet (ORCID: https://orcid.org/0000-0002-8077-1299)
- Pragya Shukla (ORCID: https://orcid.org/0000-0003-2904-750X)
- Mayank Tripathi
- Gurupreet Singh Gill
- Chandan Kumar
Institutions
- Homi Bhabha National Institute (IN)
- Tata Memorial Hospital (IN)
Publication Details
- Journal
- Journal of Gastrointestinal Cancer
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1007/s12029-025-01317-6
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00