MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress
MFN2 may play a protective role in PD by regulating mitochondrial function, ferroptosis, inflammation and oxidative stress-related factors, providing a new theoretical basis and potential therapeutic targets for the treatment of PD.
Authors
- Yunzhou Yang (ORCID: https://orcid.org/0000-0002-8604-1748)
- Ping Zhong (ORCID: https://orcid.org/0000-0002-3370-8000)
- Mingfen Song (ORCID: https://orcid.org/0000-0003-2655-4899)
- Yong Liu (ORCID: https://orcid.org/0000-0001-6227-4494)
- Haibo Zhai (ORCID: https://orcid.org/0000-0001-8585-9559)
- Bo Fang (ORCID: https://orcid.org/0009-0003-3847-5765)
- Xiuqin Wang (ORCID: https://orcid.org/0000-0001-8490-4362)
- Yan Cheng (ORCID: https://orcid.org/0000-0002-8139-6275)
Institutions
- Anhui Medical University (CN)
- Lu'an First People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fnagi.2025.1611958
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00