Vitamin A deficiency attenuates cardiac rupture in Stra6-deficient hearts following ischemic injury
The present study identifies an unexpected role for VitAD, which preserves Wnt signaling and attenuates cardiac rupture in <i>Stra6</i>-deficient hearts following ischemic injury.
Authors
- Natali Froese
- Jan C. Kamp (ORCID: https://orcid.org/0000-0002-5002-409X)
- Norbert B. Ghyselinck (ORCID: https://orcid.org/0000-0003-4042-6818)
- Lavinia Neubert (ORCID: https://orcid.org/0000-0003-4130-4185)
- Johann Bauersachs (ORCID: https://orcid.org/0000-0002-9341-117X)
- Melanie Ricke‐Hoch (ORCID: https://orcid.org/0000-0001-5479-2275)
- Christian Riehle (ORCID: https://orcid.org/0000-0002-0040-4254)
- Dirk Wedekind (ORCID: https://orcid.org/0000-0002-4027-9662)
- Steven Roger Talbot (ORCID: https://orcid.org/0000-0002-9062-4065)
- Robert Geffers (ORCID: https://orcid.org/0000-0003-4409-016X)
- Paolo Galuppo (ORCID: https://orcid.org/0000-0001-6745-5681)
- Christopher Werlein (ORCID: https://orcid.org/0000-0002-7694-4257)
- Sergej Erschow
- Heike Bähre (ORCID: https://orcid.org/0000-0001-9319-733X)
- Anna Gigina
- Yannick Smolenski
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Medizinische Hochschule Hannover (DE)
- Institut de génétique et de biologie moléculaire et cellulaire (FR)
- Helmholtz Centre for Infection Research (DE)
- German Center for Lung Research (DE)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fcvm.2025.1626769
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft