Heightened Revision Risk After Ankle Ligament Repair in Patients With Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder: A Propensity-Matched National Database Study

This study highlights the significant challenges in surgical management of ankle instability in patients with EDS and HSD. The risk of surgical failure increases over time, with a 3.1-fold increase in revision surgery rates at 5 years postoperatively compared with matched controls. These findings emphasize the need for specialized surgical approaches and comprehensive perioperative care to address the unique risks in this population. Future work should compare specific repair techniques and graft choices in this high-risk cohort.

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Publication Details

Journal
Foot & Ankle International
Published
2025-09-15
DOI
https://doi.org/10.1177/10711007251363246
Primary Topic
Tendon Structure and Treatment
Type
article
Field-Weighted Citation Impact
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article

Heightened Revision Risk After Ankle Ligament Repair in Patients With Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder: A Propensity-Matched National Database Study

Brett D. Owens, Raymond Y. Hsu, John Milner, Alan H. Daniels et al.
Foot & Ankle International
Tendon Structure and Treatment
article

Heightened Revision Risk After Ankle Ligament Repair in Patients With Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder: A Propensity-Matched National Database Study

Brett D. Owens, Raymond Y. Hsu, John Milner, Alan H. Daniels, Stephen Marcaccio, Timothy A. Reiad, Alexa Bosco, Jacob M. Johnson, Peter V Dinh, David Bruni
article en

Abstract

This study highlights the significant challenges in surgical management of ankle instability in patients with EDS and HSD. The risk of surgical failure increases over time, with a 3.1-fold increase in revision surgery rates at 5 years postoperatively compared with matched controls. These findings emphasize the need for specialized surgical approaches and comprehensive perioperative care to address the unique risks in this population. Future work should compare specific repair techniques and graft choices in this high-risk cohort.

Foot & Ankle InternationalVol. 46(11)
Providence College (US), Brown University (US), University Orthopedics Center (US)
Openalex Percentile: Top 67%
Tendon Structure and Treatment
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Heightened Revision Risk After Ankle Ligament Repair in Patients With Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder: A Propensity-Matched National Database Study — Brett D. Owens, Raymond Y. Hsu, et al. · Foot & Ankle International (2025) | TGRS Research Map | TGRS