Correlates of Derived Cannabis Product Awareness, Knowledge, Use, and Use Intentions Among Young Adults

Derived psychoactive cannabis products (DPCPs) are chemically synthesized and intoxicating. Despite their widespread use, factors associated with DPCP use remain largely unknown. We analyzed 2023 survey data among 4,031 U.S. young adults (48.9% past-month cannabis use per study design). Multivariable regressions examined sociodemographics in relation to DPCP awareness (yes/no) and patterns of DPCP knowledge, derived based on latent class analysis on five questions. Sociodemographics and DPCP knowledge class were assessed in relation to past-month DPCP use and future use intentions. Results indicated 67.1% were aware of DPCPs and 24.4% reported past-month DPCP use. DPCP knowledge classes were all correct (20.5%), mostly incorrect (36.9%), mostly unsure (21.9%), and all unsure (20.7%). Participants more aware of DPCPs were typically White (vs. Asian), male, residing in states where nonmedical cannabis was illegal, and reported past-month cannabis or cannabidiol (CBD) use. Being Black or Asian (vs. White) or Hispanic was associated with knowledge classes of "mostly incorrect" or "unsure" (vs. all correct). Correlates of using DPCPs: all correct knowledge (vs. all unsure), nonmedical cannabis illegal, female, and past-month cannabis or CBD use. Correlates of higher DPCP use intentions: all correct knowledge (vs. all unsure), nonmedical cannabis illegal, older, White (vs. multiracial), and past-month cannabis or CBD use. In sum, White participants were more aware and knowledgeable of DPCPs; participants in the "all correct" knowledge class had higher odds of DPCP use and higher use intentions, despite correctly knowing that DPCPs lacked regulations. Findings highlight the need for targeted prevention and intervention efforts and DPCP bans.