Associations between suicide attempts and clinical, metabolic, and inflammatory markers in Chinese patients with long-term schizophrenia
Female gender, greater depressive severity, and elevated metabolic and proinflammatory markers (specifically TC and IL-1β) were independently associated with increased risk of SA in Chinese patients with long-term SCZ. These findings suggest that future interventions targeting metabolic and inflammatory pathways may hold promise for preventing SA in this population.
Authors
- Lewei Liu
- Huanzhong Liu (ORCID: https://orcid.org/0000-0002-4645-4353)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-1105-9417)
- Xianhu Yao
- Xu Zhang (ORCID: https://orcid.org/0000-0003-4499-2331)
- Lei Xia (ORCID: https://orcid.org/0000-0002-0409-6148)
- Wenzheng Li (ORCID: https://orcid.org/0000-0001-5127-2813)
- Lili Zhao (ORCID: https://orcid.org/0009-0005-3037-1704)
Institutions
- Anhui Medical University (CN)
- Third People's Hospital of Hefei (CN)
- Anhui Mental Health Center (CN)
- Fourth Affiliated Hospital of Anhui Medical University (CN)
- Hefei First People's Hospital (CN)
- Anshan Hospital (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fpsyt.2025.1651246
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00