Neoadjuvant chemoimmunotherapy for esophageal squamous cell carcinoma with non-regional cervical lymph node metastasis: a retrospective pilot study
nCIT induces a high cervical nodal response in ESCC with non-regional CLNM and may redefine surgical eligibility for patients with non-regional metastases. The observed 1-year DFS of 91.7% is promising, though long-term outcomes require further validation through prospective studies.
Authors
- Wenyu Zhai
- Guozhen Yang
- Weihua Wu (ORCID: https://orcid.org/0000-0003-0157-9782)
- Lingyu Tan
- Kun Li (ORCID: https://orcid.org/0000-0001-7133-8648)
- Li Liu (ORCID: https://orcid.org/0000-0001-9685-6599)
- Wei Wei Liu (ORCID: https://orcid.org/0009-0003-2424-4990)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-3309-9209)
- Jianhua Fu (ORCID: https://orcid.org/0009-0002-6607-9068)
- Xu Zhang (ORCID: https://orcid.org/0000-0003-0347-8029)
- Xiaodong Su (ORCID: https://orcid.org/0000-0002-5956-2126)
- Chufeng Zeng
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1611108
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01