Pristinamycin-antibiotic combinations against methicillin-resistant Staphylococcus aureus recovered from skin infections
This study highlights the high prevalence of MRSA isolates recovered from various skin infections. Linezolid, vancomycin, teicoplanin, pristinamycin, chloramphenicol, and doxycycline remain effective therapeutic options. Macrolide and methicillin resistance are increasingly developing among S. aureus clinical isolates. The pristinamycin combination with doxycycline or levofloxacin was mostly synergistic and recommended for clinical evaluation.
Authors
- Khaled M. Aboshanab (ORCID: https://orcid.org/0000-0002-7608-850X)
- Abdallah M Samy (ORCID: https://orcid.org/0000-0003-3978-1134)
- Nasser S. M. Ismail (ORCID: https://orcid.org/0000-0002-5119-9318)
- Samar S. Mabrouk (ORCID: https://orcid.org/0000-0001-8647-7587)
- Sally T. K. Tohamy
- Amr S Bishr
- Muath Suliman (ORCID: https://orcid.org/0000-0001-6638-2433)
Institutions
- Ain Shams University (EG)
- Al-Azhar University (EG)
- Ahram Canadian University (EG)
- King Khalid University (SA)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1186/s12879-025-11433-0
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ain Shams University
- Science and Technology Development Fund