Predictors of acute and late diarrhea in the treatment of anal cancer with concurrent chemoradiotherapy

No dosimetric or clinical predictors of late diarrhea were found and only a trend was found between higher dose to bowel and risk of acute diarrhea. Treatment with 5-FU/Capecitabine showed a notable association with acute diarrhea. No contouring method was superior in predicting diarrhea.

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Publication Details

Journal
Acta Oncologica
Published
2025-09-15
DOI
https://doi.org/10.2340/1651-226x.2025.43975
Primary Topic
Colorectal and Anal Carcinomas
Type
article
Field-Weighted Citation Impact
0.00

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article

Predictors of acute and late diarrhea in the treatment of anal cancer with concurrent chemoradiotherapy

Sofia Spampinato, Karen‐Lise Garm Spindler, Patrik Sibolt, Katrine Smedegaard Storm et al.
Acta Oncologica
Colorectal and Anal Carcinomas
article

Predictors of acute and late diarrhea in the treatment of anal cancer with concurrent chemoradiotherapy

Sofia Spampinato, Karen‐Lise Garm Spindler, Patrik Sibolt, Katrine Smedegaard Storm, Gitte Fredberg Persson, Eva Serup‐Hansen, Camilla Kronborg, C.F. Behrens, Sif Homburg
article en

Abstract

No dosimetric or clinical predictors of late diarrhea were found and only a trend was found between higher dose to bowel and risk of acute diarrhea. Treatment with 5-FU/Capecitabine showed a notable association with acute diarrhea. No contouring method was superior in predicting diarrhea.

Acta OncologicaVol. 64
University of Copenhagen (DK), Aarhus University (DK), Aarhus University Hospital (DK), Copenhagen University Hospital (DK), Gentofte Hospital (DK), Centre for Cosmology and Particle Physics Phenomenology (DK), Danish Pain Research Center (DK), Erasmus MC Cancer Institute (NL), Technical University of Denmark (DK)
Aarhus Universitet, Aarhus Universitetshospital, Gentofte Hospital
Openalex Percentile: Top 60%
Colorectal and Anal Carcinomas
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