An Fe(<scp>ii</scp>) complex detects hydrogen peroxide with <sup>1</sup>H and <sup>19</sup>F magnetic resonance imaging responses
We report the fluorinated quinol-containing ligand, 1,8-bis(2,5-dihydroxy-4-fluorobenzyl)-1,4,8,11-tetraazacyclotetradecane (F<sub>2</sub>H<sub>4</sub>qp4), and its highly water- and air-stable Fe(II) complex. Upon oxidation by H<sub>2</sub>O<sub>2</sub>, the <sup>19</sup>F MRI signal of the complex decays while its <sup>1</sup>H MRI contrast increases; these spectroscopic responses enable the complex to ratiometrically detect H<sub>2</sub>O<sub>2</sub>.
Authors
- Alicja Franke (ORCID: https://orcid.org/0000-0002-6318-7429)
- Christian R. Goldsmith (ORCID: https://orcid.org/0000-0001-7293-1267)
- Ronald J. Beyers (ORCID: https://orcid.org/0000-0003-1522-9580)
- Ivana Ivanović‐Burmazović (ORCID: https://orcid.org/0000-0002-1651-3359)
- Sana Karbalaei (ORCID: https://orcid.org/0000-0003-1040-2962)
- P. Raj Pokkuluri (ORCID: https://orcid.org/0000-0001-5301-9483)
- Achim Zahl (ORCID: https://orcid.org/0000-0002-0321-5336)
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Tuskegee University (US)
- Ludwig-Maximilians-Universität München (DE)
- Auburn University (US)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04066c
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00