Circular RNA Cdr1as Modulates Macrophage-Mediated Cardiac Reparative Function

Circ-cdr1as plays a crucial role in regulating the anti-inflammatory phenotype of macrophages through modulation of microRNA 7 and its target gene KLF4. Therefore, circ-cdr1as holds potential as an anti-inflammatory regulator in tissue inflammation postcardiac injury.

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Publication Details

Journal
Circulation Research
Published
2025-09-16
DOI
https://doi.org/10.1161/circresaha.125.326377
Primary Topic
Circular RNAs in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Circular RNA Cdr1as Modulates Macrophage-Mediated Cardiac Reparative Function

Vandana Mallaredy, Amit Kumar, Darukeshwara Joladarashi, Charan Thej Gurrala et al.
Circulation Research
Circular RNAs in diseases
article

Circular RNA Cdr1as Modulates Macrophage-Mediated Cardiac Reparative Function

Vandana Mallaredy, Amit Kumar, Darukeshwara Joladarashi, Charan Thej Gurrala, Maria Cimini, Cindy Benedict, Venkata N Garikipati, May Trungcao, Carolina González
article en

Abstract

Circ-cdr1as plays a crucial role in regulating the anti-inflammatory phenotype of macrophages through modulation of microRNA 7 and its target gene KLF4. Therefore, circ-cdr1as holds potential as an anti-inflammatory regulator in tissue inflammation postcardiac injury.

Circulation ResearchVol. 137(9)
Temple University (US)
Openalex Percentile: Top 78%
Circular RNAs in diseases
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