Targeting IL-16 to Protect Angiotensin II–induced Hypertension and Renal Injury
Collectively, these findings indicate that T-cell-derived IL-16 exacerbates Ang II-induced hypertension and associated organ damage by promoting a T helper 1-macrophage-driven proinflammatory response.
Authors
- Ji‐Guang Wang (ORCID: https://orcid.org/0000-0001-8511-1524)
- Wuwei Rong (ORCID: https://orcid.org/0000-0003-0257-1678)
- M.-F. Li (ORCID: https://orcid.org/0009-0003-0315-2464)
- Yi-Hang Yang (ORCID: https://orcid.org/0009-0006-1461-3002)
- Zhouchun Shang (ORCID: https://orcid.org/0000-0002-1740-7961)
- Wen-Hui Zhai (ORCID: https://orcid.org/0009-0002-6380-2257)
- Xiaodong Li (ORCID: https://orcid.org/0000-0002-3771-6286)
- Xiao-Hui Chen
- Jiajia Zhao
- Qian-Wan Deng (ORCID: https://orcid.org/0009-0002-9309-8352)
- Zumin Xu (ORCID: https://orcid.org/0000-0002-4701-9177)
- Pingjin Gao (ORCID: https://orcid.org/0000-0002-7750-3314)
Institutions
- World Wide Web Consortium (US)
- Shanghai Institute of Hypertension (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- Hypertension
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25172
- Citations
- 2
- Primary Topic
- Whipple's Disease and Interleukins
- Type
- article
- Field-Weighted Citation Impact
- 2.94