Allyl Syringate

Syringic acid (1) is a naturally occurring compound with diverse biological activities. Structural modification of syringic acid often enhances its utility; however, the spectroscopic data for several derivatives remain unreported, and the procedures to obtain them can be synthetically challenging. In this study, we report the allylation of syringic acid (1) to afford a novel derivative, allyl syringate (1c). The structure of this compound was confirmed by IR, NMR, and MS spectroscopy and compared with those of closely related derivatives (1a and 1b). These findings provide a useful foundation for further studies on the allylation of syringic acid and related phenolic acid derivatives.

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Publication Details

Journal
Molbank
Published
2025-09-15
DOI
https://doi.org/10.3390/m2060
Primary Topic
Microbial Natural Products and Biosynthesis
Type
article
Field-Weighted Citation Impact
0.00

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article

Allyl Syringate

Nawasit Chotsaeng, Naruedech Thimpa, Suriyaphong Poprom, Laksakarn Songpao
Molbank
Microbial Natural Products and Biosynthesis
article

Allyl Syringate

Nawasit Chotsaeng, Naruedech Thimpa, Suriyaphong Poprom, Laksakarn Songpao
article en

Abstract

Syringic acid (1) is a naturally occurring compound with diverse biological activities. Structural modification of syringic acid often enhances its utility; however, the spectroscopic data for several derivatives remain unreported, and the procedures to obtain them can be synthetically challenging. In this study, we report the allylation of syringic acid (1) to afford a novel derivative, allyl syringate (1c). The structure of this compound was confirmed by IR, NMR, and MS spectroscopy and compared with those of closely related derivatives (1a and 1b). These findings provide a useful foundation for further studies on the allylation of syringic acid and related phenolic acid derivatives.

MolbankVol. 2025(3)
King Mongkut's Institute of Technology Ladkrabang (TH)
King Mongkut's Institute of Technology Ladkrabang
Openalex Percentile: Top 72%
Microbial Natural Products and Biosynthesis
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