Yerba Mate ( <i>Ilex paraguariensis A. St.‐Hil.</i> ) Reduces Oxidative Stress and Bone Resorption in Apical Periodontitis
In vitro, YM suppressed pro-inflammatory cytokines and NF-κB, inhibited osteoclastogenesis and was cytocompatible. In vivo, it reversed AP-induced redox state and reduced inflammation and bone resorption, suggesting therapeutic promise.
Authors
- Murilo Catelani Ferraz (ORCID: https://orcid.org/0000-0002-1199-5950)
- Carolina de Barros Morais Cardoso (ORCID: https://orcid.org/0000-0002-4943-7022)
- Edílson Ervolino (ORCID: https://orcid.org/0000-0003-4859-0583)
- Renan Dal‐Fabbro (ORCID: https://orcid.org/0000-0002-4125-8441)
- Luciano Tavares Ângelo Cintra (ORCID: https://orcid.org/0000-0003-2348-7846)
- Paulo César Ciarlini (ORCID: https://orcid.org/0000-0003-1480-5208)
- Marco C. Bottino (ORCID: https://orcid.org/0000-0001-8740-2464)
- Caroline Anselmi (ORCID: https://orcid.org/0000-0002-3189-1542)
- Cristiane Cantiga da Silva (ORCID: https://orcid.org/0000-0003-4313-7149)
- Carolina Sayuri Wajima (ORCID: https://orcid.org/0000-0003-3629-4904)
Institutions
- University of Michigan (US)
- Centro Universitário de Araraquara (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1111/iej.70031
- Citations
- 1
- Primary Topic
- Heavy Metals in Plants
- Type
- article
- Field-Weighted Citation Impact
- 0.75