Performance of an Idiopathic Pulmonary Fibrosis–Derived Multibiomarker Panel for Rheumatoid Arthritis–Associated Interstitial Lung Disease
A multibiomarker panel derived from IPF-associated biomarkers was associated with RA-ILD in separate development and validation cohorts. This overlap supports the concept of shared etiopathogenesis of IPF and RA-ILD and illustrates the potential for peripheral blood biomarker panels to stratify ILD risk among patients with RA.
Authors
- Katherine D. Wysham (ORCID: https://orcid.org/0000-0001-8707-7649)
- Dana P. Ascherman (ORCID: https://orcid.org/0000-0002-1387-0860)
- Gail S. Kerr (ORCID: https://orcid.org/0000-0002-4930-3235)
- Punyasha Roul
- Gary A. Kunkel
- Scott M. Matson (ORCID: https://orcid.org/0000-0002-3748-9597)
- Andreas Reimold
- Jill A. Poole (ORCID: https://orcid.org/0000-0002-6236-2563)
- Geoffrey M. Thiele (ORCID: https://orcid.org/0000-0001-5688-8596)
- Daniel J. Kass (ORCID: https://orcid.org/0000-0001-6597-7830)
- Brent A. Luedders (ORCID: https://orcid.org/0000-0001-6717-9680)
- Paul A. Monach (ORCID: https://orcid.org/0000-0003-4937-0515)
- Ted R. Mikuls (ORCID: https://orcid.org/0000-0002-0897-2272)
- Bryant R. England (ORCID: https://orcid.org/0000-0002-9649-3588)
- Yangyuna Yang
- Grant W. Cannon (ORCID: https://orcid.org/0000-0001-6640-9173)
- Michael J. Duryee (ORCID: https://orcid.org/0000-0001-9104-2238)
- Joshua F. Baker (ORCID: https://orcid.org/0000-0003-0170-028X)
- Halie Frideres (ORCID: https://orcid.org/0009-0008-1752-0949)
Institutions
- Howard University (US)
- University of Kansas (US)
- University of Pittsburgh (US)
- Georgetown University (US)
- University of Washington (US)
- University of Utah (US)
- VA Boston Healthcare System (US)
- The University of Kansas Health System (US)
- VA Salt Lake City Healthcare System (US)
- VA Puget Sound Health Care System (US)
- VA North Texas Health Care System (US)
- University of Kansas Medical Center (US)
- Philadelphia VA Medical Center (US)
- Washington DC VA Medical Center (US)
- VA Nebraska Western Iowa Health Care System (US)
- Seattle University (US)
- University of Nebraska Medical Center (US)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
- Philadelphia University (US)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1002/art.43383
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- U.S. Department of Veterans Affairs
- Amgen
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Rheumatology Research Foundation
- CSL Behring
- Regeneron Pharmaceuticals
- National Institutes of Health
- Clinical Science Research and Development
- National Institute for Occupational Safety and Health