Prevalence, Determinants, and Outcomes of Low Disease Activity and Remission Attainment in Patients With Systemic Lupus Erythematosus That Is Clinically Active
In patients with SLE with clinical disease activity, the proportion attaining LLDAS and DORIS under usual care conditions is suboptimal. Longer maintenance of these states is significantly associated with reduced risk of flare. Because flares and damage accrual still occur frequently following initial target attainment, further research is needed to inform strategies for maintaining these targets.
Authors
- Sean O’Neill (ORCID: https://orcid.org/0000-0002-6739-832X)
- Annie Law (ORCID: https://orcid.org/0000-0003-3301-0603)
- Chak Sing Lau (ORCID: https://orcid.org/0000-0001-6698-8355)
- Cherica Tee (ORCID: https://orcid.org/0000-0002-0766-0189)
- Masayoshi Harigai (ORCID: https://orcid.org/0000-0002-6418-2603)
- Kristine Ng (ORCID: https://orcid.org/0009-0006-6225-2715)
- Mandana Nikpour (ORCID: https://orcid.org/0000-0002-6585-5611)
- Jun Kikuchi (ORCID: https://orcid.org/0000-0002-6809-394X)
- Yoshiya Tanaka (ORCID: https://orcid.org/0000-0002-0807-7139)
- Shereen Oon (ORCID: https://orcid.org/0000-0002-6822-5711)
- Sandra Navarra (ORCID: https://orcid.org/0000-0003-0094-8654)
- Sang‐Cheol Bae (ORCID: https://orcid.org/0000-0003-4658-1093)
- Eric Francis Morand (ORCID: https://orcid.org/0000-0002-9507-3338)
- Zhanguo Li (ORCID: https://orcid.org/0000-0002-2590-6242)
- Nicola Tugnet
- Alberta Hoi (ORCID: https://orcid.org/0000-0002-9416-7383)
- Madelynn Chan (ORCID: https://orcid.org/0000-0002-8102-7664)
- Naoaki Ohkubo (ORCID: https://orcid.org/0000-0003-2265-4104)
- Vera Golder (ORCID: https://orcid.org/0000-0001-5691-4344)
- Leonid Zamora (ORCID: https://orcid.org/0000-0002-4209-4442)
- Yeong‐Jian Jan Wu (ORCID: https://orcid.org/0000-0002-5444-4729)
- Yasuhiro Katsumata (ORCID: https://orcid.org/0000-0003-1654-0119)
- Fiona Goldblatt (ORCID: https://orcid.org/0000-0001-7205-4807)
- Shirley Chiu Wai Chan (ORCID: https://orcid.org/0000-0002-0640-0676)
- Zhuoli Zhang (ORCID: https://orcid.org/0000-0001-7219-9141)
- Yanjie Hao (ORCID: https://orcid.org/0000-0001-8715-259X)
- Worawit Louthrenoo (ORCID: https://orcid.org/0000-0003-3105-6122)
- Jiacai Cho (ORCID: https://orcid.org/0000-0002-4477-3430)
- BMDB Basnayake
- Laniyati Hamijoyo (ORCID: https://orcid.org/0000-0002-1310-674X)
- Rangi Kandane‐Rathnayake (ORCID: https://orcid.org/0000-0001-5397-1482)
- Tsutomu Takeuchi (ORCID: https://orcid.org/0000-0003-1111-8218)
- Michael Tee (ORCID: https://orcid.org/0000-0003-0113-8290)
- Aisha Lateef (ORCID: https://orcid.org/0000-0002-0838-7495)
- Sunil Kumar (ORCID: https://orcid.org/0000-0001-9905-4831)
- Yi‐Hsing Chen (ORCID: https://orcid.org/0000-0002-8135-9554)
- Dylan Hansen (ORCID: https://orcid.org/0000-0001-5777-7476)
- Sargunan Sockalingam
- Shue Fen Luo
Institutions
- University of Santo Tomas Hospital (PH)
- The University of Sydney (AU)
- The University of Melbourne (AU)
- Chinese University of Hong Kong (HK)
- University of Occupational and Environmental Health Japan (JP)
- Peking University (CN)
- Keio University (JP)
- Singapore General Hospital (SG)
- Royal Prince Alfred Hospital (AU)
- Middlemore Hospital (NZ)
- Liverpool Hospital (AU)
- Tan Tock Seng Hospital (SG)
- Teaching Hospital Kandy (LK)
- Flinders Medical Centre (AU)
- University of Malaya (MY)
- Dr. Hasan Sadikin General Hospital (ID)
- St Vincent's Hospital Melbourne (AU)
- Taichung Veterans General Hospital (TW)
- Greenlane Clinical Centre (NZ)
- Taoyuan Chang Gung Memorial Hospital (TW)
- St Vincent’s Private Hospital Sydney (AU)
- Waitemata District Health Board (NZ)
- Peking University People's Hospital (CN)
- Peking University First Hospital (CN)
- Tokyo Women's Medical University (JP)
- Hanyang University Seoul Hospital (KR)
- Woodlands Health Campus (SG)
- National University Hospital (SG)
- Chiang Mai University (TH)
- Monash University (AU)
- University of the Philippines Manila (PH)
- University of Hong Kong (HK)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1002/acr.25640
- Primary Topic
- Lysosomal Storage Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Eli Lilly and Company
- AstraZeneca
- GlaxoSmithKline
- National Research Foundation
- University of Sydney
- University of Melbourne
- National Research Foundation of Korea
- AstraZeneca Australia
- EMD Serono
- Medical Research Council
- National Health and Medical Research Council
- Janssen Research and Development