Efficacy and Safety of Extended-Release Acetazolamide Capsules for the Prevention of Acute Mountain Sickness: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial
Once-daily extended-release acetazolamide (500 mg) effectively prevents AMS and is well-tolerated in healthy Asian individuals. This regimen may enhance adherence and serve as a practical prophylactic option for high-altitude travelers.
Authors
- Luobu Gesang (ORCID: https://orcid.org/0009-0008-3269-3362)
- Zejuan Wang
- Quzong Zhaxi (ORCID: https://orcid.org/0000-0001-6674-6743)
- Quzhen Gesang
- Cong Wei (ORCID: https://orcid.org/0000-0003-2310-9255)
- Zhuoga Danzeng
- Yangzong Suona
- Rui Zhang (ORCID: https://orcid.org/0009-0009-8928-6853)
- Xiaona Liu
- Jin Wang
- C. Baima
- Binyun Liu
- Bai Ci
- Qiangba Dingzeng
- Zhuoga Baima
- Zhuoma Ciren
Institutions
- Xizang Minzu University (CN)
- Defence Institute of High Altitude Research (IN)
- Aerospace Center Hospital (CN)
- Tibet Autonomous Region People's Hospital (CN)
Publication Details
- Journal
- High Altitude Medicine & Biology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1177/15578682251375409
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00