Precision Dosing of Meropenem in a Neonate on CARPEDIEM Dialysis: A Grand Round
This case highlights the successful application of model-informed precision dosing to individualize meropenem therapy in a critically ill neonate with liver failure on CARPEDIEM dialysis. MIPD is a valuable tool for dose adjustment in patients with unique and unpredictable pharmacokinetics.
Authors
- Stuart L. Goldstein (ORCID: https://orcid.org/0000-0003-3711-8785)
- Horace Rhodes Hambrick (ORCID: https://orcid.org/0000-0003-1218-8293)
- Emily Diseroad
- Sonya Tang Girdwood (ORCID: https://orcid.org/0000-0001-7737-8499)
- Erin E. Schuler
- Tamara K. Hutson
- Ronaldo Morales (ORCID: https://orcid.org/0000-0002-5856-3717)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Lurie Children's Hospital (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1097/ftd.0000000000001382
- Citations
- 1
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 1.39