Comparing the immunogenicity of intradermal and intramuscular vaccination of elderly with BNT162b2 XBB.1.5: An equivalent dose study
No differences were found in antibody level and functionality following ID and IM administration of 20 μg BNT162b2 XBB.1.5 vaccine in elderly, while IM administration was less reactogenic than ID administration.
Authors
- Lucille F. van Beek (ORCID: https://orcid.org/0000-0002-7126-2580)
- Leo G. Visser (ORCID: https://orcid.org/0000-0002-3600-9782)
- Anna H.E. Roukens (ORCID: https://orcid.org/0000-0002-1397-0992)
- Xuehui He (ORCID: https://orcid.org/0000-0002-3801-4091)
- Hans de Graaf (ORCID: https://orcid.org/0000-0001-8055-8749)
- Christa E. van der Gaast-de Jongh
- Marien Isaäk de Jonge (ORCID: https://orcid.org/0000-0003-2812-5895)
- Dimitri A. Diavatopoulos (ORCID: https://orcid.org/0000-0001-7065-7807)
- Marije S Koks
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- Vaccine
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127749
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Radboud Universitair Medisch Centrum
- European Regional Development Fund