The analysis of the gut microbiome during liver disease progression led to the identification of biomarkers for related mild cognitive impairment
In this context, maintaining a balanced production of fecal SCFA is more important than individual concentrations. The downregulation of specific microbial metabolic pathways, along with the presence of certain bacterial species, holds promise as early-stage biomarkers and highlights the potential of microbiome-targeted strategies for monitoring and managing liver-related cognitive impairment.
Authors
- Víctor Hugo Jarquín‐Díaz (ORCID: https://orcid.org/0000-0003-3758-1091)
- Lola Giner-Pérez (ORCID: https://orcid.org/0000-0003-4695-8460)
- Gaspar Pérez-Martı́nez (ORCID: https://orcid.org/0000-0003-3501-1626)
- Jennifer N. Martínez-Medina (ORCID: https://orcid.org/0000-0003-3438-5730)
- Juan Gallego (ORCID: https://orcid.org/0000-0003-4368-5284)
- Amparo Urios (ORCID: https://orcid.org/0000-0003-2699-7040)
- Sofia Kirke Forslund (ORCID: https://orcid.org/0000-0003-4285-6993)
- Alessandra Fiorillo (ORCID: https://orcid.org/0000-0002-2125-8241)
- Carmina Montoliú (ORCID: https://orcid.org/0000-0002-4740-4788)
- Franc Casanova‐Ferrer (ORCID: https://orcid.org/0000-0001-7427-1987)
- Alicia Salvador (ORCID: https://orcid.org/0000-0002-8686-8083)
- Salvador Benlloch (ORCID: https://orcid.org/0000-0002-0794-6937)
- Desamparados Escudero‐García (ORCID: https://orcid.org/0000-0001-7351-3307)
- Vicente Felipo (ORCID: https://orcid.org/0000-0003-3145-9538)
- Carla Giménez‐Garzó (ORCID: https://orcid.org/0000-0002-9748-443X)
- Yaiza M. Arenas (ORCID: https://orcid.org/0000-0001-6769-5888)
- Daniela Batallas (ORCID: https://orcid.org/0009-0002-1677-023X)
- Adrià López‐Gramaje (ORCID: https://orcid.org/0009-0007-3784-8637)
Institutions
- Universitat de València (ES)
- Max Delbrück Center (DE)
- Universidad Cardenal Herrera CEU (ES)
- Instituto de Salud Carlos III (ES)
- Humboldt-Universität zu Berlin (DE)
- Hospital Clínico Universitario de Valencia (ES)
- Instituto de Agroquímica y Tecnología de Alimentos (ES)
- Hospital Arnau de Vilanova (ES)
- INCLIVA Health Research Institute (ES)
- Centro de Investigacion Principe Felipe (ES)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3389/fmicb.2025.1670512
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71