Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment
These preliminary findings suggest that alterations in nasal microbiota may be linked to olfactory impairment and mucosal structural changes in MS. While P. buccalis emerged as a potential microbial correlate of olfactory dysfunction, its role remains unclear and may reflect secondary ecological shifts. Further mechanistic studies and larger cohorts are needed to determine causality and assess the diagnostic or therapeutic value of nasal microbiome features in MS.
Authors
- Lan Chu (ORCID: https://orcid.org/0000-0002-1004-0300)
- Zhuoma Danzhen
- Yang Zhang (ORCID: https://orcid.org/0000-0003-4521-9228)
- Yao Li (ORCID: https://orcid.org/0000-0001-8249-8989)
- Junyu Zhu
- Zidan Gao
Institutions
- Guiyang Medical University (CN)
- Guizhou University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1002/acn3.70181
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Commission of Guizhou Province
- National Natural Science Foundation of China
- Fudan University
- Huashan Hospital
- Guizhou Medical University