The Effect Of Eccentric Training On Cardiovascular Responses On Parkinson's Disease Patients

HISTORY:Four Parkinson’s disease (PD) patients (72.25 + 4.4 yrs) began experiencing motor and sensory changes within 10 years of their participation in this exercise treatment. These included unbalanced gait, a slight left-hand tremor with reduced and slower range of motion, a loss of smell, and excess saliva accumulation. All of these patients sought medical help as their functional abilities had regressed from the Parkinson’s condition rather than aging. PHYSICAL EXAMINATION: Along with self-reported symptoms, a physical examination identified left-sided bradykinesia and rigidity. A diagnosis of Parkinson’s disease (PD) was made and subsequently confirmed by a second source. DIFFERENTIAL DIAGNOSIS: 1. Motor/Neurological impairment 2. PD TEST AND RESULTS: The study examined the effects of eccentric lower body exercise on PD symptoms. During exercise, participants stood upright on a solid platform that moved in an elliptical path in the sagittal plane while absorbing all motion with their lower extremities. All four patients completed a two times per week training for fourteen weeks. All sessions consisted of three 45-second exercise bouts while assessing workload intensity utilizing the Borg Rate of Perceived Exertion (RPE) Scale (1-10), with two minutes of standing rest between bouts. Physiological data was recorded pre- and post-exercise during each session. A paired t-test analysis was utilized with significance established at p < 0.05. Post-training resting HR (76 + 8.2 bpm) was 5% lower than pre-training resting HR (81 + 8.1 bpm). Post-systolic resting BP (121 + 5.4 mmHg) was 8% lower than pre-systolic resting BP (131.5 + 2.2 mmHg) after training (p = 0.02). Post-diastolic resting BP (76.5 + 3.3 mmHg) was 5% lower than pre-diastolic BP (81 + 2.5 mmHg) after training. Heart rates increased with each successive exercise bout, although there was no difference between pre- and post-training. Post-training exercise bout three RPE value (4.25 + 0.63) was 30% higher than initial training exercise bout three value (3.0 + 0.71). FINAL/WORKING DIAGNOSIS: PD with improved gross motor function TREATMENT AND OUTCOMES: 1. Continued eccentric lower body training 2. Expansion and increase intensity of physical activities 3. Continued monitoring of functional parameters 4. Reduction in prescription use of Sinemet