Feasibility of Velocity-Selective ASL MRA at 5T

Motivation: Ultra-high field (UHF) provides improved SNR that benefits velocity-selective arterial spin labeling (VSASL) MRA; however, the sensitivity of VS prepulses to B0 and B1 inhomogeneities may render VS ASL MRA impractical. Goal(s): This study aims to assess the feasibility of VS ASL MRA for human brain at 5T. Approach: Double-refocused hyperbolic-secant (DRHS) module, B1-independent rotation (BIR)-4 module, and BIR-8 module based VS ASL MRA were implemented and compared at 5T. Results: The VS ASL MRA utilizing BIR-4 or BIR-8 modules at 5T had decent image quality, although there exist subtraction errors in static tissues. Impact: The study suggests that VS ASL MRA at 5T is feasible.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2025-09-16
DOI
https://doi.org/10.58530/2025/3701
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Feasibility of Velocity-Selective ASL MRA at 5T

Xianyi Zhang, Zhensen Chen, Haiyan Wang, Xijing Zhang et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Advanced MRI Techniques and Applications
article

Feasibility of Velocity-Selective ASL MRA at 5T

Xianyi Zhang, Zhensen Chen, Haiyan Wang, Xijing Zhang, Lixin Liu, Jiayu Zhu, LI Hong-we, Ziqi Sun
article en

Abstract

Motivation: Ultra-high field (UHF) provides improved SNR that benefits velocity-selective arterial spin labeling (VSASL) MRA; however, the sensitivity of VS prepulses to B0 and B1 inhomogeneities may render VS ASL MRA impractical. Goal(s): This study aims to assess the feasibility of VS ASL MRA for human brain at 5T. Approach: Double-refocused hyperbolic-secant (DRHS) module, B1-independent rotation (BIR)-4 module, and BIR-8 module based VS ASL MRA were implemented and compared at 5T. Results: The VS ASL MRA utilizing BIR-4 or BIR-8 modules at 5T had decent image quality, although there exist subtraction errors in static tissues. Impact: The study suggests that VS ASL MRA at 5T is feasible.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 63%
Advanced MRI Techniques and Applications
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Feasibility of Velocity-Selective ASL MRA at 5T — Xianyi Zhang, Zhensen Chen, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2025) | TGRS Research Map | TGRS