Andrographolide Protects Against Liver Cancer by Suppressing the AKT-mTOR Pathway & GPX4 Protein to Induce Ferroptosis
Andrographolide is a potential drug to alleviate liver cancer by inducing ferroptosis in the cancer cells. In this article, a series of experiments would be conducted to test whether it has positive results on cancer killing. In addition, we would find out the mechanism between Andrographolide and ferroptosis. Furthermore, methods would also be used to identify the target site of Andrographolide inside the human body. Those possible outcomes in this article could help to a creative understanding of how Andrographolide inhibits hepatoma.
Authors
- J. Zhang (ORCID: https://orcid.org/0000-0001-9297-3659)
Institutions
- Sun Yat-sen University (CN)
Publication Details
- Journal
- Theoretical and Natural Science
- Published
- 2025-09-09
- DOI
- https://doi.org/10.54254/2753-8818/2025.au26868
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00