Andrographolide Protects Against Liver Cancer by Suppressing the AKT-mTOR Pathway & GPX4 Protein to Induce Ferroptosis

Andrographolide is a potential drug to alleviate liver cancer by inducing ferroptosis in the cancer cells. In this article, a series of experiments would be conducted to test whether it has positive results on cancer killing. In addition, we would find out the mechanism between Andrographolide and ferroptosis. Furthermore, methods would also be used to identify the target site of Andrographolide inside the human body. Those possible outcomes in this article could help to a creative understanding of how Andrographolide inhibits hepatoma.

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Publication Details

Journal
Theoretical and Natural Science
Published
2025-09-09
DOI
https://doi.org/10.54254/2753-8818/2025.au26868
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Andrographolide Protects Against Liver Cancer by Suppressing the AKT-mTOR Pathway & GPX4 Protein to Induce Ferroptosis

J. Zhang
Theoretical and Natural Science
Ferroptosis and cancer prognosis
article

Andrographolide Protects Against Liver Cancer by Suppressing the AKT-mTOR Pathway & GPX4 Protein to Induce Ferroptosis

J. Zhang
article en

Abstract

Andrographolide is a potential drug to alleviate liver cancer by inducing ferroptosis in the cancer cells. In this article, a series of experiments would be conducted to test whether it has positive results on cancer killing. In addition, we would find out the mechanism between Andrographolide and ferroptosis. Furthermore, methods would also be used to identify the target site of Andrographolide inside the human body. Those possible outcomes in this article could help to a creative understanding of how Andrographolide inhibits hepatoma.

Theoretical and Natural ScienceVol. 135(1)
Sun Yat-sen University (CN)
Openalex Percentile: Top 64%
Ferroptosis and cancer prognosis
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