Computational Identification of RNF114 nsSNPs with Potential Roles in Psoriasis and Immune Dysregulation

In the current study, we predicted three novel, potentially pathogenic RNF114 variants with protein-destabilizing effect that could lead to immune dysregulation.

Authors

Mahfod Aldoseri (ORCID: https://orcid.org/0000-0002-4004-4468)
Ebtihal Kamal
Ghalia Mahfod Aldoseri
Arwa Ibrahim Alwabran
Ghanem Mahfod Aldoseri

Institutions

Prince Sattam Bin Abdulaziz University (SA)

Publication Details

Journal: Medical Sciences
Published: 2025-09-16
DOI: https://doi.org/10.3390/medsci13030194
Primary Topic: Cytokine Signaling Pathways and Interactions
Type: article
Field-Weighted Citation Impact: 0.00

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article

Computational Identification of RNF114 nsSNPs with Potential Roles in Psoriasis and Immune Dysregulation

Mahfod Aldoseri, Ebtihal Kamal, Ghalia Mahfod Aldoseri, Arwa Ibrahim Alwabran et al.

Sep 16, 2025

Medical Sciences

Cytokine Signaling Pathways and Interactions

article

Computational Identification of RNF114 nsSNPs with Potential Roles in Psoriasis and Immune Dysregulation

Mahfod Aldoseri, Ebtihal Kamal, Ghalia Mahfod Aldoseri, Arwa Ibrahim Alwabran, Ghanem Mahfod Aldoseri

September 16, 2025article en

Abstract

In the current study, we predicted three novel, potentially pathogenic RNF114 variants with protein-destabilizing effect that could lead to immune dysregulation.

Medical SciencesVol. 13(3)

Prince Sattam Bin Abdulaziz University (SA)

Openalex Percentile: Top 66%

Cytokine Signaling Pathways and Interactions

DOI Open Access PDF OpenAlex

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Computational Identification of RNF114 nsSNPs with Potential Roles in Psoriasis and Immune Dysregulation — Mahfod Aldoseri, Ebtihal Kamal, et al. · Medical Sciences (2025) | TGRS Research Map | TGRS